Oxygen delivery (DO₂) quantifies the total amount of oxygen delivered to peripheral tissues per minute. It depends on cardiac output and arterial oxygen content (CaO₂). Critical DO₂ (<330 mL/min) may indicate supply-dependency and hemodynamic compromise.
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Results
CaO₂ (Arterial O₂ Content) —
DO₂ (O₂ Delivery) —
DO₂ Classification —
CvO₂ (Venous O₂ Content) —
VO₂ (O₂ Consumption) —
O₂ Extraction Ratio —
Formula
CaO₂ = (Hgb × 1.34 × SaO₂/100) + (0.0031 × PaO₂) [mL O₂/dL]
Reference Values
Parameter Normal Value Clinical Significance CaO₂ 18–21 mL O₂/dL Arterial oxygen content DO₂ 950–1150 mL O₂/min Total O₂ delivery to tissues VO₂ 200–250 mL O₂/min Tissue O₂ consumption O₂ Extraction Ratio 20–30% >50% suggests O₂ debt Critical DO₂ ~330 mL O₂/min Supply-dependency threshold
Clinical Notes
Optimizing DO₂: Increase Hgb (transfusion if <7–8 g/dL), improve SaO₂ (supplemental O₂, mechanical ventilation), or increase cardiac output (fluids, inotropes).O₂ Extraction Ratio >50% suggests tissues are compensating for low DO₂ — early sign of circulatory shock. SvO₂ <60% is a concerning threshold.
For educational use only. Not a substitute for clinical judgment.
