Cardiac Arrest — Pediatric Epinephrine
Dose Formula0.01 mg/kg IV/IO
Calculated Dose—
Volume (1:10,000)—
Volume (1:1,000)—
Maximum Dose1 mg (10 mL of 1:10,000)
Repeat Q3–5 min. IV/IO route preferred. 1:10,000 concentration recommended for IV use.
Anaphylaxis — IM Epinephrine
Dose Formula0.01 mg/kg IM
Calculated Dose—
Volume (1:1,000)—
Maximum Dose0.5 mg (0.5 mL of 1:1,000)
Anterolateral thigh preferred. May repeat Q5–15 min. EpiPen Jr (0.15 mg) for 15–30 kg; EpiPen (0.3 mg) for >30 kg.
Dose Range Table
Initial dose: 0.05–0.1 mcg/kg/min. Titrate to hemodynamic response. Central access preferred.
Croup — Nebulized Racemic Epinephrine
Dose: 0.5 mL of 2.25% racemic epinephrine solution
Diluent: Add to 2.5 mL normal saline for nebulization
Route: Nebulizer mask — all pediatric patients regardless of weight
Fixed dose for croup. Monitor for rebound (symptoms may return 2–3h post-treatment). Observe minimum 2–4h after administration. If racemic epi unavailable: L-epinephrine 5 mL of 1:1000 (5 mg) via nebulizer.
⚠ For educational/reference use only. Verify doses with clinical pharmacist and current institutional protocols.
