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Nephrology / Renal
eGFR (CKD-EPI)

eGFR — CKD-EPI 2021

Race-free Chronic Kidney Disease Epidemiology Collaboration equation

Patient Parameters
Enter a valid creatinine (0.1–30)
Enter age 18–120
— mL/min/1.73m²
CKD Staging & Drug Dosing Implications
StageeGFR (mL/min/1.73m²)DescriptionDrug Dosing Impact
G1≥ 90Normal or highStandard dosing
G260–89Mildly decreasedMonitor; minimal dose adjustment
G3a45–59Mild-moderately decreasedAdjust renally-cleared drugs
G3b30–44Moderate-severely decreasedReduce doses; avoid nephrotoxins
G415–29Severely decreasedSignificant reductions; prepare for RRT
G5< 15Kidney failureDialysis doses; many drugs contraindicated
CKD-EPI 2021 Formula (race-free):
κ = 0.7 (F) or 0.9 (M)  |  α = −0.241 (F) or −0.302 (M)
eGFR = 142 × min(Scr/κ, 1)α × max(Scr/κ, 1)−1.200 × 0.9938Age × 1.012 [if female]
Clinical Notes: CKD-EPI 2021 is preferred over MDRD and the 2009 race-based equation. It is more accurate at higher GFR values. CKD staging requires confirmation over ≥3 months. eGFR should be used alongside albuminuria (ACR) for complete CKD classification.
⚕️ For qualified healthcare professionals only. Not a substitute for clinical judgment.

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