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Hematology / Electrolytes
Corrected Calcium

Corrected Calcium Calculator

Hematology / Electrolytes

Total serum calcium is bound to albumin. When albumin is low, measured calcium underestimates true calcium. This calculator corrects total calcium for hypoalbuminemia using the Payne formula.
Formula
Corrected Ca = Measured Ca + 0.8 × (4.0 − Albumin)
Ionized Ca ≈ Corrected Ca / 2.0 (estimate only)
Reference
ConditionCorrected CalciumNotes
Severe Hypocalcemia<7.5 mg/dLTetany, seizures risk
Hypocalcemia7.5–8.5 mg/dLSymptoms may occur
Normal8.5–10.5 mg/dL—
Hypercalcemia10.5–12 mg/dL—
Significant Hypercalcemia12–14 mg/dLUrgent evaluation
Hypercalcemic Crisis>14 mg/dLEmergency
Clinical Notes
Hypocalcemia causes: Hypoparathyroidism, vitamin D deficiency, pancreatitis, CKD, magnesium deficiency, bisphosphonates.

Hypercalcemia causes: Primary hyperparathyroidism (most common outpatient), malignancy (most common inpatient), vitamin D toxicity, sarcoidosis, thiazide diuretics, milk-alkali syndrome.
For educational use only. Clinical decisions must incorporate full patient evaluation.

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